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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
16.36
Human Site:
S341
Identified Species:
36
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
S341
L
N
Y
L
Q
H
L
S
L
S
R
C
Y
D
I
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
R299
L
Q
H
L
S
L
S
R
C
Y
D
I
I
P
E
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
S339
L
N
Y
L
Q
H
L
S
L
S
R
C
Y
D
I
Dog
Lupus familis
XP_546346
749
81658
S666
L
N
Y
L
Q
H
L
S
L
S
R
C
Y
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
S341
L
N
Y
L
Q
H
L
S
L
S
R
C
Y
D
I
Rat
Rattus norvegicus
Q9QZH7
276
30442
L197
L
V
R
G
C
G
G
L
K
A
L
F
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
C361
L
I
Y
L
Q
H
L
C
L
S
R
C
Y
Q
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
D400
C
P
Q
L
L
E
L
D
L
S
D
C
N
S
L
Honey Bee
Apis mellifera
XP_395497
484
54314
S404
V
R
S
L
L
D
L
S
K
L
E
H
L
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
S358
K
Q
L
D
L
S
D
S
T
S
L
T
Y
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
W281
V
K
N
K
H
E
M
W
R
A
V
K
K
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
33.3
20
N.A.
20
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
N.A.
80
N.A.
N.A.
N.A.
40
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% A
% Cys:
10
0
0
0
10
0
0
10
10
0
0
55
0
0
0
% C
% Asp:
0
0
0
10
0
10
10
10
0
0
19
0
0
37
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
10
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
10
10
0
0
0
0
0
0
10
10
% G
% His:
0
0
10
0
10
46
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
46
% I
% Lys:
10
10
0
10
0
0
0
0
19
0
0
10
10
10
10
% K
% Leu:
64
0
10
73
28
10
64
10
55
10
19
0
19
0
19
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
37
10
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
19
10
0
46
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
10
0
0
0
0
10
10
0
46
0
0
0
0
% R
% Ser:
0
0
10
0
10
10
10
55
0
64
0
0
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% T
% Val:
19
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
0
0
0
10
0
0
55
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _